Decoder with Nilay Patel Decoder with Nilay Patel

JB Pritzker thinks AI could help us live to 100 — or threaten us like nukes

Oct 19, 2026 · 59m

Topics discussed

Sponsorships and episode introduction Keeping the Bears in Illinois Political realignment and antitrust AI job displacement and economic upheaval State competition for tech jobs and incentives Government structure and the AI cabinet Using AI to navigate state bureaucracy AI expertise in state government Sponsor break: Upwork AI in cybersecurity and phishing Decision-making frameworks for governors Lessons from the pandemic response Privacy, surveillance, and the post-COVID shift Illinois AI safety and privacy laws License plate readers and public backlash AI in healthcare and therapy regulations Sponsor breaks: CrowdStrike and Framer Federal privacy law and state laboratories Data centers, NIMBYism, and energy costs Generational change in political leadership Social media regulation and school phone bans AI existential risk and nuclear analogies AGI consciousness and industry disagreement Outro and credits
Listen ad-free on Castria